Yes, in terms of presidential elections, we may be in the wilderness for a couple of decades. We really need pro-secession governors in red states, but from the disaster result in the Alabama special election, looks like there are too many nimrods to allow it.
Neither party has ever been denied the White House for that long, and it's not going to start now. The political pendulum inevitably swings back to the other side after a couple of terms, and it will do so again.
You've got to stop and reflect on how much strife this administration has brought to the country. A majority of the public are going to be eager to give the other guys a chance to restore a sense of calm and security after eight years of "fundamental transformation".