There are people who want to unwisely drive faster than the speed limit.
Speeding is inherently hazardous to others. Drug use is not; it can be hazardous to others when combined with other acts, e.g. driving, but that's no more an argument for banning drugs than it is for banning driving.
Supposed hyper-inflated drug prices are only a concern to the criminal drug users transferring their money to the criminal drug sellers.
Clearly false - once they're in criminal hands they're a concern to every potential victim of the criminals' enhanced resources for crime.
Article VI of the U.S. Constitution contains the supremacy clause, which makes federal laws the supreme law of the land and forces states to follow the U.S. Constitution and all federal laws
And the U.S. Constitution limits the federal government to explicitly enumerated powers that don't include banning within-state drug making, transporting, selling, or using.