Posted on 03/10/2013 7:51:21 PM PDT by null and void
The new drugs are synthetic versions of resveratrol which is found in red wine and is believed to have an anti-ageing effect as it boosts activity of a protein called SIRT1.
Pharmaceutical giant GlaxoSmithKline has been testing the medications on patients suffering with medical conditions including cancer, diabetes and heart disease.
The work proves that a single anti-ageing enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.
The most common naturally-occurring activator is resveratrol, which is found in small quantities in red wine, but synthetic activators with much stronger activity are already being developed.
Despite this, there have already been promising results in some trials with implications for cancer, cardiovascular disease and cardiac failure, type 2 diabetes, Alzheimer's and Parkinson's diseases, fatty liver disease, cataracts, osteoporosis, muscle wasting, sleep disorders and inflammatory diseases such as psoriasis, arthritis and colitis.
Professor Sinclair said: 'In the history of pharmaceuticals, there has never been a drug that tweaks an enzyme to make it run faster.'
Four thousand synthetic activators, which are 100 times as potent as a single glass of red wine, have been developed - with the best three being used in human trials.
While any drug would be strictly prescribed for certain conditions, Professor Sinclair suggests that one day, they could be taken orally as a preventative.
They could therefore be used in the same way as statin drugs are commonly prescribed to prevent, instead of simply treating, cardiovascular disease.
In animal models, overweight mice given synthetic resveratrol were able to run twice as far as slim mice and they lived 15 per cent longer.
'Some of us could live to 150, but we won't get there without more research.'
(Excerpt) Read more at dailymail.co.uk ...
Imagine having to listen to Jimmy Carter natter on about his crap for another 70 years.
They'll just bump the age to claim it up to 145 or so...
Nah. Only the political elite will have the drug. Obamas death panels will have to shorten the lives of the rest of us to make up for the increased resource usage by the then longer lived political elite.
kkk....kris kringle kat
“Grandfather, it’s not healthy to live to be such an old age” {Windwalker}
Absolute total disaster unless they are able to stop all dementia, Alzheimers, and related neurological breakdowns first.
I can not imagine dealing with a dementia patient for 80+ years.
“Why would I want to live until 150?”
Why not...if you were healthy and disease free...
‘Moses’ attributes (Deuteronomy 34:7)...
Fully ambulatory...
Jack LaLane abs...
Full mental prowess...
Eyes, ears and nose fully functional...
‘And Moses was an hundred and twenty years old when he died: his eye was not dim, nor his natural force abated.’
(Deuteronomy 34:7 KJV)
“I think I hold the resveratrol until the long-term effects of high doses of are better known.”
But it might take 150 years or so to find out if it works...you gotta try it to know... :)
Meanwhile, Pino Noir has the most of the good resveratrol stuff...a glass every hour or so could make life a lot more interesting while you wait to decide on the ‘treatment’...
At his 70th birthday party, Ike quipped, "People ask, 'Who wants to live to be 100?'.....the man who's 99."
And there's the point of all the hype. The good doctor wants more $$$$$ for research.
Other parts of the bible give man’s age at 3score and 10. That’s 70, but if of good strength (this part is paraphrasing) may make it to 80.) This body breaks down and if your not in good health, who needs to be 150. Not even the rich can stop aging, just delay it a few years. Howard Hughes is a example of being alive, but his late years were not pleasant....
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