She’s commenting on a public figure.
John Goodman is John Candy waiting to happen.
Goodman looks lately like he’s lost a lot of weight (what alliteration!). We just don’t know when our time is up. The great John Candy had lost a father and a brother at a very young age. It made him - unfortunately - very fatalistic. Some of this is genetic.
I don’t think John Candy was an alcoholic like John Goodman is/was.