Since flumazenil antagonized the effects of benzodiazepines, they thought there were specific benzodiazepine receptors.
1 posted on
11/24/2012 11:24:51 PM PST by
neverdem
To: neverdem
Did that neurologist think to recommend patients to an endocrinologist to have calcium and parathyroid levels checked?
2 posted on
11/24/2012 11:37:10 PM PST by
wastedyears
(I don't want to live on this planet anymore.)
To: neverdem
Many years ago I was reading "The Schwartzbein Principle". Schwartzbein discussed sleep issues and said that "GABA" helps "reduce the noise in your head" so you can sleep. I often find myself writing software algorithms instead of normal "dreaming". It's very productive the next day, but often results in being damn tired instead of being rested. On a whim, I picked up a bottle of GABA to evaluate the effects. It turned my normal mental machinations into a full blown circus. A bit like the kind of rave you might see in a heavy metal night club in an over the top Hollywood movie. I certainly didn't sleep well at all. About 6 weeks later, I tested it again. Same effect. GABA does not turn down the "noise" in my head. It might as well be a brass band playing. It turns up the noise for me.
When I'm forced out of bed before I'm adequately rested, I'm tired all day. I just blew off making the 900 mile drive home for Thanksgiving because my employer sent me to a very expensive security training class, then my niece stole the only sleep day I was going to get for a memorial for her dad. 11 days of forced 6:30 AM starts with work finishing at midnight to 1 AM. I was too burned out to safely drive.
3 posted on
11/25/2012 12:11:57 AM PST by
Myrddin
To: neverdem
Many years ago I was reading "The Schwartzbein Principle". Schwartzbein discussed sleep issues and said that "GABA" helps "reduce the noise in your head" so you can sleep. I often find myself writing software algorithms instead of normal "dreaming". It's very productive the next day, but often results in being damn tired instead of being rested. On a whim, I picked up a bottle of GABA to evaluate the effects. It turned my normal mental machinations into a full blown circus. A bit like the kind of rave you might see in a heavy metal night club in an over the top Hollywood movie. I certainly didn't sleep well at all. About 6 weeks later, I tested it again. Same effect. GABA does not turn down the "noise" in my head. It might as well be a brass band playing. It turns up the noise for me.
When I'm forced out of bed before I'm adequately rested, I'm tired all day. I just blew off making the 900 mile drive home for Thanksgiving because my employer sent me to a very expensive security training class, then my niece stole the only sleep day I was going to get for a memorial for her dad. 11 days of forced 6:30 AM starts with work finishing at midnight to 1 AM. I was too burned out to safely drive.
4 posted on
11/25/2012 12:12:10 AM PST by
Myrddin
To: neverdem; John Robinson
FR is double posting tonight.
5 posted on
11/25/2012 12:15:30 AM PST by
Myrddin
To: neverdem; Myrddin
Thanks again neverdem, your posts contain a ton of interesting info!
Myrddin...if I’m understanding correctly, what you experience with GABA supplementation is the opposite of what it’s ‘sposed to be. Like Ritalin(!?) for hyperactivity - GABA is causing a paradoxical reaction in you. That’s very interesting.
Could it be the source of supplementation that’s “off”? IDK, but I feel for you. There are lists of various GABA-containing foods, I wonder if your reaction to them would be different?
Also, I’m not as up with the research, but I wonder if it’s a GABA problem, or a hyperactive GABA RECEPTOR problem.
I agree with the poster who mentioned checking endocrine function...
just me, but I’d go for blood testing with an eye toward ‘treatment’ with whole food supplements...YMMV.
FRegards,
spank
10 posted on
11/25/2012 8:17:41 AM PST by
spankalib
(The downside of liberty is the need to tolerate those who despise it.)
To: neverdem
Who's to say what's normal, but maybe we're not doing it right, or at least not as we used to.
Look up "First sleep and Second sleep" for another idea about how we might be wired and why some of us struggle with going back to sleep.
12 posted on
11/25/2012 8:56:23 AM PST by
GBA
(Here in the Matrix, life is but a dream.)
To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
25 posted on
11/25/2012 11:03:07 PM PST by
neverdem
( Xin loi min oi)
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