DFMO caused hearing loss so doctors didn’t want to use it.
It wasn’t the FDA, it was the clinicians. They are restarting the trials with longer, lower doses. My dad died of colon cancer.
The problem is that the press screams “Miracle cure!” when they have no clue how the trials are conducted. It may have worked with a person or two but not everyone. DFMO’s effects turned out to be modest.
A good friend of mine died from it also.
OK, so here’s your choicea.
Die.
Lose (not even proven yet) a bit of your hearing.
Need I ask?
Same deal with the EDTA Chelation studies. Started around 2001. Supposed to be a seven or ten year study, whatever.
Latest I hear is it’s still going on, any release of initial results are being delayed yada yada yada even though EDTA has been KNOWN to be an effective treatment for some forms of heart problems since like NINETEEN TWENTY OR SO...!!!