There are, and many are somewhere along the line in the process of leaving. The departures are being tracked very accurately by Pr. David Barnhard at http://davidbarnhart.blogspot.com
About 300 congregations and clery have departed for the one-year old North American Lutheran Church www.thenalc.org.
A slightly larger number have departed for the ten year old Lutheran Congregations in Mission for Christ www.lcmc.net.
I am only aware of one ELCA to LCMS move, a congregation in the NYC suburbs served by a Pastor who had been Seminex/AELC.
Two issues: Women Pastors and Open Communion. The Missouri Synod does not approve of either. Most of those leaving the ELCA who found the homosexuality thing too liberal are themselves still liberal on the ordination of women and on Communion fellowship.