[Myrddin]

Not yet. I'm starting to see some impacts in the middle joint of my little finger. It's the spine, knees and ankles that are most annoying. During my daytime hours, I'm focused on work and can just endure the. Not so when I'm trying to sleep. I put down 4 x 200 mg ibuprofen about 30 minutes before hitting the rack so I can get to sleep.

A co-worker whose wife has all manner of auto-immune problems has reported good result with methotrexate. I simply haven't sought any treatment beyond OTC, but I know it is going to get ahead of me at some point.

[neverdem]

I put down 4 x 200 mg ibuprofen about 30 minutes before hitting the rack so I can get to sleep.

That's not a small dose. OTC meds are not necessarily benign. They can be more than problematic.

http://www.drugs.com/pro/ibuprofen.html

[Calm_Cool_and_Elected]

I’ve been on Methotrexate for almost 17 yrs now and have tolerated it well. I’ve been getting an “experimental” drug that has helped me tremendously. It does something to the B cells which are what is causing my disease to at least be active. This drug has been approved for RA and will hopefully be approved for what I have soon.