Sears explains the protective nature of the fat reserves in this book. When the fat cells can no longer buffer the toxic fats, the toxic fats enter the blood stream and begin to invade vital organs. That sets off a fairly rapid downward spiral of health problems.
Thanks for the information and link to the book. Very interesting — I think there is definitely something to this inflammation theory.
I did some search and a lot of medical articles came up on this topic.
Here is one:
Inflammation, stress, and diabetes