Posted on 12/31/2009 7:25:21 PM PST by neverdem
Abstract
A brief overview of methods for reprogramming to induced pluripotency and of the properties of induced pluripotent stem cells.
Introduction
What is induced pluripotency?
Pluripotency—the ability to make all cell types of the body—is a property possessed by a few cells in the early mammalian embryo, those belonging to the blastocyst inner cell mass. Embryonic stem (ES) cells are derived by in vitro culture of the inner cell mass and are also pluripotent. As the embryo develops, its cells become progressively more specialized and pluripotency is lost, although somatic tissues retain what are called multipotent cells (or adult stem cells) that can give rise to cells of a particular developmental lineage.
It has been known for some years that it is possible to reverse this process of progressive specialization and render more mature cells pluripotent. If the nucleus of a mature cell is exposed to the cytoplasm of a pluripotent cell by fusing the cells, for instance, it begins to show markers of pluripotency. Or, if a mature nucleus is introduced into an enucleated egg—a process called somatic cell nuclear transfer—the nucleus is reprogrammed to an embryonic state and the resulting zygote can go on to create an entire organism. Recently, a more defined way to render mature cells pluripotent was described. Named induced pluripotency and first described in 2006, this approach requires the heterologous overexpression of just a few key transcription factors in the cell for a period of a few weeks. In a process that remains mechanistically still mysterious and, with current methods, also notably inefficient, the mature cell is returned to an embryonic stem cell-like pluripotent state and is named an induced pluripotent stem (iPS) cell.
Making induced pluripotent stem cells
Methods to make induced pluripotent stem cells are still developing rapidly, but some themes are...
(Excerpt) Read more at nature.com ...
IMHO, neverdem:
While your article sounds scholarly and scientific and all that; the whole embryonic stem cell crusade has been, and still is, a giant hoax. NOTHING good, even after a number of years of flogging the notion, has ever come from EMBRYONIC stem cell research. Meanwhile, MANY cures, and potential cures have been realized from the use of mature stem cells, placenta blood cells, etc.
I personally believe the devotees of the death culture; those who hold abortion as THE paramount holy sacrament of their godless religion, are merely pushing embryonic stem cell usage in order to create a MARKET for the by-products of abortion; e.g., the aborted baby, from which the ghouls can scavenge body parts, cells, etc., and SELL them.
I could be wrong, but I have a suspicion that many of the beauty products on the market today, which tout COLLAGEN as their main component, MAY actually contain collagen from aborted babies. I hope I’m wrong.
ROTFL!
This being said after a story about induced pluripotency, a technique that developed from discoveries made during embryonic stem-cell research!
And please...learn the difference between cells "from aborted babies" and cells derived from a line from discarded fetal tissue.
What happens when you take a Viagra pill.
induced pluripotency?
I got that from drinking the water
in Puerto Viagra.
Are fetuses the only place you can get these things?
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