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Women at risk from vitamin A deficiency
Newcastle University ^ | 18-Nov-2009 | Dr. Georg Lietz

Posted on 11/18/2009 6:00:21 AM PST by Pharmboy

Almost half of UK women could be suffering from a lack of vitamin A due to a previously undiscovered genetic variation, scientists at Newcastle University have found.

The team, led by Dr Georg Lietz, has shown that almost 50 per cent of women have a genetic variation which reduces their ability to produce sufficient amounts of vitamin A from beta-carotene.

Vitamin A – also known as retinol – plays a vital role in strengthening our immune system, protecting us against common infections such as flu and winter vomiting.

Vitamin A also helps to maintain healthy skin and mucus linings such as inside the nose and the lungs.

In 1987, an American study found that excessive use of vitamin A during pregnancy was associated with certain birth defects. Beta-carotene, however, was deemed to be safe and this led to the general advice that we should eat more of this nutrient, allowing the body to convert what it needs into vitamin A.

However, Dr Lietz' latest research – published in the FASEB Journal and presented this month at the 2nd Hohenheim Nutrition Conference in Stuttgart – shows that for many women, beta-carotene is not an effective substitute for vitamin A.

Dr Lietz explained: "Vitamin A is incredibly important – particularly at this time of year when we are all trying to fight off the winter colds and flu.

"It boosts our immune system and reduces the risk of inflammation such as that associated with chest infections.

"What our research shows is that many women are simply not getting enough of this vital nutrient because their bodies are not able to convert the beta-carotene."

From a volunteer group of 62 women, the team found that 29 of them – 47 per cent – carried the genetic variation which prevented them from being able to effectively convert beta-carotene into vitamin A.

The study also showed that all volunteers consumed only about a third of their recommended intake from 'preformed' vitamin A – the form found in dairy products such as eggs and milk – indicating that those volunteers carrying the genetic variation were not eating enough vitamin A-rich foods to reach the optimum level their body required to function.

"Worryingly, younger women are at particular risk," explained Dr Lietz, who is based in the School of Agriculture, Food and Rural Development at Newcastle University.

"The older generations tend to eat more eggs, milk and liver which are naturally rich in vitamin A whereas the health-conscious youngsters on low-fat diets are relying heavily on the beta-carotene form of the nutrient."

The next step in the study is to assess whether the effect of the genetic variation can also be observed in men and whether our body composition will influence our ability to absorb and convert beta-carotene into vitamin A.

###


TOPICS: Extended News; News/Current Events; United Kingdom
KEYWORDS: nutrition; vitamina
Beta carotene is what makes carrots orange, and is two molecules of (active) vitamin A bonded together. The body splits the bond and we get vitamin A when that occurs. The takeaway here is that supplements with small amounts of active A are a good idea.
1 posted on 11/18/2009 6:00:22 AM PST by Pharmboy
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To: Pharmboy

Why did they test only women? Is there any reason to believe that the same problem does not also occur in men?


2 posted on 11/18/2009 6:05:10 AM PST by hellbender
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To: Pharmboy
For anyone else who was curious about the "winter vomiting" thing...

Winter vomiting virus

Norwalk by any other name :)

3 posted on 11/18/2009 6:08:57 AM PST by mewzilla (Voter fraud is treason.)
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To: hellbender
Why did they test only women?

"Eh, what's up, doc?"

Probably because pregnant women have been told to lay off the vitamin A.

4 posted on 11/18/2009 6:11:12 AM PST by decimon
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To: hellbender

Why did they test only women? Is there any reason to believe that the same problem does not also occur in men?

Because only women matter, doofus!


5 posted on 11/18/2009 6:13:01 AM PST by Chickensoup (SHRUGGING shrugging SHRUGGING shrugging SHRUGGING shrugging SHRUGGING)
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To: decimon
Ha! I was just going to ping you...
6 posted on 11/18/2009 6:20:38 AM PST by Pharmboy (The Stone Age did not end because they ran out of stones...)
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To: Chickensoup

Ah yes. The same reason they spend much more on research on breast cancer than on prostate cancer, even though deaths from each are about the same, IIRC.


7 posted on 11/18/2009 6:21:14 AM PST by hellbender
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To: blam; SunkenCiv; Coleus; aculeus; wagglebee

Pinging the (vitamin) A list...


8 posted on 11/18/2009 6:22:29 AM PST by Pharmboy (The Stone Age did not end because they ran out of stones...)
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To: Pharmboy
the form found in dairy products such as eggs and milk

Cows lay eggs? Who knew?

9 posted on 11/18/2009 6:39:42 AM PST by Tax-chick (Buy me a "Land Shark" and take me to Anguilla.)
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To: Tax-chick
the form found in dairy products such as eggs and milk

Cows lay eggs? Who knew?

No need to be chicken-milk about that.

10 posted on 11/18/2009 6:43:49 AM PST by decimon
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To: Pharmboy
Ha! I was just going to ping you...

"Eh, thanks, doc."

11 posted on 11/18/2009 6:45:02 AM PST by decimon
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To: Pharmboy
Pinging the (vitamin) A list...

Who knew?

12 posted on 11/18/2009 6:58:47 AM PST by aculeus
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To: aculeus
Pinging the (vitamin) A list...

Who knew?

But don't knock it. This is the only A list I could hope to make.

13 posted on 11/18/2009 7:08:20 AM PST by decimon
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To: decimon

LOL!


14 posted on 11/18/2009 7:22:47 AM PST by Tax-chick (Buy me a "Land Shark" and take me to Anguilla.)
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To: Pharmboy

i always thought that taking more than 10,000 i.u. of vitamin-a can cause birth defects


15 posted on 11/18/2009 1:31:12 PM PST by Coleus (Abortion, Euthanasia & FOCA - - don't Obama and the Democrats just kill ya!)
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To: Coleus; decimon
Well, a bit higher than that, but that's the number they have always used as a safe top. But, as decimom said above, that fear could be the reason for the deficiency.

It is also interesting to note that Accutane (for acne) is a derivative of vitamin A (a type of retinoic acid) and will almost ALWAYS cause birth defects when taken early in the pregnancy.

16 posted on 11/18/2009 1:57:41 PM PST by Pharmboy (The Stone Age did not end because they ran out of stones...)
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To: hellbender

Ah yes. The same reason they spend much more on research on breast cancer than on prostate cancer, even though deaths from each are about the same, IIRC.

You are not going to be very well-liked if you keep THIS up!


17 posted on 11/19/2009 7:18:12 AM PST by Chickensoup (SHRUGGING shrugging SHRUGGING shrugging SHRUGGING shrugging SHRUGGING)
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To: Chickensoup

http://www.breastcancernews.brighterplanet.org/breast-cancer-news/why-is-the-federal-government-us-spending-7x-more-on-breast-cancer-research-than-prostate-cancer-despite

Why is the federal government (US) spending 7x more on breast cancer research than prostate cancer, despite…
…the fact that about 9 percent more men in the US develop prostate cancer than women develop breast cancer.
$550 million v. $80 million
http://www.worldnetdaily.com/news/articl…;
Likewise, in Australia, breast cancer on average kills 2600 women each year
However,
http://www.prostate.org.au/pcfa-reso…n…;
Prostate cancer kills 2,700 Australian men every year.
2600 women v. 2700 men. Yet the Australian Government, in 2004, through the National Health and Medical Research Council, provided $6.9 million in funding for research into breast Cancer. While the Australian Government, through the National Health and Medical Research Council, provided $2.5 million in funding for research into prostate cancer.
$6.9 m for women; $2.5 m for men.
Women receiving 3x more funding than men.
My question is WHY
Are men just not worth as much as women?
Ladies first? But I thought we lived in an age of equality?


18 posted on 11/19/2009 10:27:07 AM PST by hellbender
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