By 1914, the Harrison Act was passed, which was the beginnings of the War on Some Drugs at the Federal level, for the reason of controlling the minorities and they were not shy about saying so...
Each drug was associated with a minority group, then demonized by saying that its usage would induce white women to have sex with the men from that group. It was really vile. Our current WoSD is less OBVIOUSLY biased, but is just as evil.
By 1914 most of the states had laws against cocaine, heroin, opium, etc and 1 in 400 US citizens were addicts.
Most of the addicts were women that were 'prescribed drugs to relieve 'women's' problems.
I think a Democrat, Wilson, was President when the Harrison Act was passed. Roosevelt, a Democrat, was President when the Marijuana Tax Act of 1937 (or whatever it was called) was passed. It seems to me that this anti drug stuff was started by the Democrats, not Conservative Republicans.