Okay, in a way this is exactly what the framers of the Constitution had in mind when they gave a few enumerated powers to the Federal Government and reserved everything else to the states and citizens. This allowed many different experiments to be tried in different regions of the country. The way the citizens of the states responded, either by throwing politicians out on their asses or by leaving the state or by accepting the innovation, would demonstrate the feasibility and/or wisdom of the project. This is also why too much federal government trying to make one-size-fits-all law on a wide variety of subjects is deadly. It reduces the diversity of a wide variety of social/economic environmental niches and makes it more and more impossible that new and better, or just different, ways of doing things can emerge to solve the wide array of problems of life.
Problem is this stuff already has it's foot in the door with various agencies in the Federal Government. FDA,EPA,HUD,Interstate Commerce “Clause” etc... all have potential “good intention” policies already enacted or ready to ponce with the right government.