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The Worm Turns
NY Times ^ | June 29, 2008 | MOISES VELASQUEZ-MANOFF

Posted on 07/03/2008 8:12:29 PM PDT by neverdem

In the early 1990s, Joel Weinstock, a gastroenterologist, encountered a puzzle. The prevalence of inflammatory bowel disease (I.B.D.) across North America increased markedly during the 20th century. Many thought that “bad” genes would eventually explain the spike, but Weinstock didn’t buy it. In areas where fewer than two generations ago the I.B.D. incidence might have been as low as 1 in 10,000, it...

--snip--

If eliminating worms led to an increase in disease, could re-introducing worms actually treat these diseases? In mice, the answer was yes. Worms were used to “inoculate” against mouse asthma, Type 1 diabetes, multiple sclerosis and I.B.D. But how to re-worm humans? We got rid of them for a reason. Too many worms can lead to anemia or obstructed bowels. The wrong kind can cause considerable suffering, even death.

Weinstock spotted a prime candidate on pig farms. Pig farmers are chronically exposed to Trichuris suis, the pig whipworm, and tolerate it with no apparent side effects. (This is not the potentially dangerous worm found in undercooked pork.)

In 2005, he published results from two human studies. After ingesting 2,500 microscopic T. suis eggs at 3-week intervals for 24 weeks, 23 of 29 Crohn’s patients responded positively. (Crohn’s disease belongs to the I.B.D. family, which also includes ulcerative colitis.) Twenty-one went into complete remission. In the second study, 13 of 30 ulcerative colitis patients improved compared with 4 in the 24-person placebo group.

Scientists around the world are intrigued. Several large studies are under way. Trials using T. suis eggs on patients with multiple sclerosis, Crohn’s and hay fever are beginning in the United States, Australia and Denmark, respectively. In Germany, scientists are planning studies on asthma and food allergies. Other European scientists, meanwhile, plan to replicate many of these experiments with Necator americanus, a human hookworm...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: autoimmunedisorders; health; helminths; medicine
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To: neverdem

I just now got to my ping list. Thanks neverdem for posting this. As you know , I have Crohn’s disease.


41 posted on 07/04/2008 4:57:40 PM PDT by afnamvet
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To: afnamvet
As you know , I have Crohn’s disease.

I wasn't sure. It's been quite a while. Happy Fourth of July!

42 posted on 07/04/2008 5:17:33 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: neverdem

Thanks very much neverdem and I hope you are having a wonderful 4th of July as well.


43 posted on 07/04/2008 6:25:02 PM PDT by afnamvet
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To: neverdem

My father in law has bad Crohn’s. He looked into this, but was to far along to do much about it.


44 posted on 07/06/2008 2:48:09 PM PDT by redgolum ("God is dead" -- Nietzsche. "Nietzsche is dead" -- God.)
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To: neverdem

Take two worms and call me in the morning - BTTT.


45 posted on 07/07/2008 9:19:38 AM PDT by OB1kNOb (ISLAM IS THE SPIRIT OF ANTICHRIST, DIRECTED BY SATAN AND HIS FALLEN MINIONS.)
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