Or, use some crafy audio/video software to change the ending so that her whine about always being asked the hard questions first is inserted with the video of her answering a phone while wearing her "serious" glasses.
Bill Clinton said this in 2004: "One of Clinton's laws of politics is this: If one candidate's trying to scare you, and the other one's trying to get you to think; if one candidate's appealing to your fears, and the other one's appealing to your hopes; you better vote for the person who wants you to think and hope."
Obama could just run Hillary's ad with that quote plastered across the screen the whole time. She'd be incinerated toast. Democrat voters would eat it up.