Free Republic
Browse · Search
News/Activism
Topics · Post Article

Skip to comments.

Scientists Find Cancer Culprits in Cigarette Smoke
Health Day Via Yahoo! ^ | 2-29-08

Posted on 02/28/2008 4:16:42 PM PST by Dysart

HURSDAY, Feb. 28 (HealthDay News) -- It's long been known that smoking causes lung cancer, but a new study is the first to show that the hydrogen peroxide in cigarette smoke is what actually causes healthy lung cells to turn cancerous.

Researchers from the University of California, Davis, said their findings may help lead to new treatments for lung cancer and may help the tobacco industry develop "safer" cigarettes by eliminating such substances in the smoke.

"With the five-year survival rate for people with lung cancer at a dismally low 15.5 percent, we hope this study will provide better insight into the identification of new therapeutic targets," senior author Tzipora Goldkorn said in a prepared statement.

In this laboratory study, the researchers exposed different sets of human lung cells to cigarette smoke or hydrogen peroxide and then incubated the cells for one to two days. The cells were then compared to unexposed airway cells. The cells exposed to cigarette smoke and those exposed to hydrogen peroxide showed the same molecular signatures of cancer development. The unexposed cells showed no such changes.

The findings are published in the March issue of The FASEB Journal, published by the Federation of American Societies for Experimental Biology.

Guns kill, bombs kill and cigarettes kill," Dr. Gerald Weissmann, editor-in-chief of The FASEB Journal, said in a prepared statement. "While biologists can't do much about the first two, studies like this will help in the fight against tobacco-related death and disease. These experiments not only pinpoint new molecular targets for cancer treatment, but also identify culprits in cigarette smoke that eventually will do the smoker in."

Cigarette smoking, which causes more than 400,000 deaths a year in the United States (about one in five of all deaths) is the leading preventable cause of premature death in the country, according to the U.S. Centers for Disease Control and Prevention. Smoking causes 90 percent of all lung cancer deaths in men and about 80 percent of lung cancer deaths in women.

Tobacco smoke contains more than 4,000 chemical compounds, including 43 that are know to cause cancer, according to a U.S. Surgeon General report released in 2000.


TOPICS: News/Current Events
KEYWORDS: cancer; cigs
Navigation: use the links below to view more comments.
first 1-2021-31 next last

1 posted on 02/28/2008 4:16:53 PM PST by Dysart
[ Post Reply | Private Reply | View Replies]

To: Dysart

We have consensus!


2 posted on 02/28/2008 4:18:05 PM PST by Izzy Dunne (Hello, I'm a TAGLINE virus. Please help me spread by copying me into YOUR tag line.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Dysart

I thought it was the benz-alpha-pyrene and methyl chrysene, who knew?

And then there was the polonium theory, and the “tar” and nicotine...


3 posted on 02/28/2008 4:19:42 PM PST by DBrow
[ Post Reply | Private Reply | To 1 | View Replies]

To: Dysart
It's long been known that smoking causes lung cancer, but a new study is the first to show that the hydrogen peroxide in cigarette smoke is what actually causes healthy lung cells to turn cancerous.

I'm sure there are a lot of very nervous blondes in the nation tonight.

4 posted on 02/28/2008 4:22:06 PM PST by Dahoser (America's great untapped alternative energy source: The Founding Fathers spinning in their graves.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Dysart
This is soooooooo true IMHO, today is my 4 month quit date, the Nicotine was a breeze it’s all the other crap, hell I had a Ammonia fit for weeks.
5 posted on 02/28/2008 4:22:26 PM PST by cmsgop ( You go to da box..... you feel shame)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Dysart
OoooooooooooKay ... what about all those H2O2-based mouth products? Seems minute traces might find their way down the airway. Cumulative damage? How long until we hear the lawyer's TV ads asking if we ever used a peroxide-based oral product?
6 posted on 02/28/2008 4:22:31 PM PST by NonValueAdded (Who Would Montgomery Brewster Choose?)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Dysart

Is the hydrogen peroxide produced in the burning process?


7 posted on 02/28/2008 4:24:21 PM PST by Rb ver. 2.0 (Global warming is the new Marxism.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: DBrow

Well, Nicotine does speed tumor growth, no doubt. But these are in growths already established.


8 posted on 02/28/2008 4:24:38 PM PST by Dysart
[ Post Reply | Private Reply | To 3 | View Replies]

To: Dysart
Hydrogen Peroxide? That's it ? Why ...just oxidize it to pure harmless water vapor and smoke to your heart's content !

Sigh.. wonder what these 'researchers' will find next to contradict this finding.

9 posted on 02/28/2008 4:24:45 PM PST by libh8er
[ Post Reply | Private Reply | To 1 | View Replies]

To: Dysart

Take it out and give the cigarettes back at a reasonable price.


10 posted on 02/28/2008 4:25:47 PM PST by donna (If America is not a Christian nation, it will be part of the Islamic nation. Take your pick.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: cmsgop
today is my 4 month quit date

Congrats. I'm at 7 months. I admit, though, my first thought when reading this was, "Take out the hydrogen peroxide and let me smoke my cigarettes again".

11 posted on 02/28/2008 4:32:00 PM PST by tnlibertarian
[ Post Reply | Private Reply | To 5 | View Replies]

To: Rb ver. 2.0; y'all
Is the hydrogen peroxide produced in the burning process?

Yes. And maybe someone more familiar with the process involving cig smoke condensation which activates HP can explain it.(Hes says hopefully) Can't imagine the formaldehyde is esp healthful either.

12 posted on 02/28/2008 4:32:46 PM PST by Dysart
[ Post Reply | Private Reply | To 7 | View Replies]

To: Dysart

Guns, without a human agent, do not kill. Most bombs, without a human agent, do not kill (there are a few unstable bombs that do detonate “on their own,” but it was a human that created that instability).


13 posted on 02/28/2008 4:33:23 PM PST by ought-six
[ Post Reply | Private Reply | To 1 | View Replies]

To: donna

“Take it out and give the cigarettes back at a reasonable price.”

Lung cancer is just one of many diseases that cigarettes cause. Cigarettes should have no place in a healthy society just like cocaine, meth, and other agents of death. With at least cocaine and meth, you can say they legally sold for profit.


14 posted on 02/28/2008 4:34:05 PM PST by sagar
[ Post Reply | Private Reply | To 10 | View Replies]

To: Dysart

Hydrogen peroxide is nothing but water with an extra O, but I guess if they can declare ozone a terrible polluntant, they can call hydrogen peroxide a carcinogen.


15 posted on 02/28/2008 4:40:17 PM PST by Eva (Benedict Arnold was a war hero, too.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: sagar
With at least cocaine and meth, you can say they legally sold for profit.

Huh?

Are you high?

16 posted on 02/28/2008 4:49:58 PM PST by Wingy
[ Post Reply | Private Reply | To 14 | View Replies]

To: Dysart

And if it turns out that the hydrogen peroxide is not present in second hand smoke ... or is significantly reduced in content by the time it gets to someone else’s nose ... then we can make a stronger case against second hand smoke being a cancer causing agent.


17 posted on 02/28/2008 4:58:12 PM PST by who_would_fardels_bear
[ Post Reply | Private Reply | To 1 | View Replies]

To: sagar
"Cigarettes should have no place in a healthy society just like cocaine, meth, and other agents of death."

If you don't like such things then don't do them. Leave the state out of it please.

18 posted on 02/28/2008 4:58:33 PM PST by KoRn (CTHULHU '08 - I won't settle for a lesser evil any longer!)
[ Post Reply | Private Reply | To 14 | View Replies]

To: sagar
Cigarettes should have no place in a healthy society just like cocaine, meth, and other agents of death.

So where does Freedom fall into your little healthy Scenerio ? while your telling us what we should be allowed to have in a healthy society what would you propose to do with those who wish to be free to do as they please healthy or no ?

Not meant to be a flame i'm just curious ....

19 posted on 02/28/2008 5:09:43 PM PST by ATOMIC_PUNK (Drink no longer water, but use a little wine for thy stomach's sake and thine often infirmities.)
[ Post Reply | Private Reply | To 14 | View Replies]

To: sagar

They are not intoxicating so it’s no one’s business.

Fat people are more expensive.


20 posted on 02/28/2008 5:12:22 PM PST by donna (If America is not a Christian nation, it will be part of the Islamic nation. Take your pick.)
[ Post Reply | Private Reply | To 14 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-31 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
News/Activism
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson