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Scientists aglow over drug for radiation poisoning
Houston Chronicle ^ | Jan 28, 2008 | Eric Berger

Posted on 01/28/2008 7:22:09 AM PST by RDTF

With the Starship Enterprise seemingly doomed after losing warp power, Mr. Spock exposes himself to lethal radiation in Star Trek II: The Wrath of Khan. After repairing the engines and saving the day, Spock dies.

Evidently, the movie's writers didn't think scientists would find a drug to cure radiation poisoning by the late 23rd century.

Yet local scientists may be on the verge of doing just that more than two centuries before the setting of the Star Trek film.

Rice University's Jim Tour and his colleagues at two Houston health institutions have found a drug that, when given to mice before radiation exposure, is 5,000 times more effective than the best-available therapy for radiation injuries.

Officials at the Department of Defense, seeking remedies for the radiation sickness that would follow a nuclear strike, were so taken by the research that they recently gave Tour a $540,000 grant and asked him to compress the next phase of testing into an almost unheard-of nine months.

In that time, Tour's research group hopes to improve the drug so it works as well when given after radiation exposure as it does before.

"They originally asked for something in six months, but I told them that was impossible," said Tour, a chemist who directs Rice's Carbon Nanotechnology Laboratory.

Radiation disrupts cells by freeing molecules from their chemical bonds and allowing them to run amok inside the nucleus.

These so-called free radicals can destroy a cell's DNA, killing the cell or preventing it from dividing. The result can be a slow death of the victim as organs fail.

To address the problem, Tour and his partners at two University of Texas institutions — the M.D. Anderson Cancer Center and the Health Science Center — have created a drug that's deceptively simple.

-snip-

(Excerpt) Read more at chron.com ...


TOPICS: Extended News; News/Current Events; US: Texas; War on Terror
KEYWORDS: dod; radiation; riceuniversity; wmd

1 posted on 01/28/2008 7:22:11 AM PST by RDTF
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To: RDTF

in before the Trek geeks.

[clear throat]

Enterprise cannon DID have a radiation drug, however it was only good up to a point.

that said,

cool.


2 posted on 01/28/2008 7:29:18 AM PST by longtermmemmory (VOTE! http://www.senate.gov and http://www.house.gov)
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To: RDTF

Every now and then a truly noteworthy headline shows up in “Latest Posts.”


3 posted on 01/28/2008 7:30:39 AM PST by Cyber Liberty (Don't trust anyone who can’t take a joke. [Congressman BillyBob])
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To: RDTF
"Typically, such a drug would take 12 to 14 years of development before coming to market at a cost of $1 billion or so."

"Tour conceded, however, that there are special circumstances surrounding the radiation drug that could accelerate its development."

"There is no alternative therapy, and the poor soul so exposed has no hope other than petitions to God," Tour said.

4 posted on 01/28/2008 7:31:29 AM PST by Sender (I've been chicken franchised.)
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To: RDTF

Thank you for this article. I was once a Health Physicist and I have to say, this is way cool!


5 posted on 01/28/2008 7:39:18 AM PST by FreeAtlanta (Search for Folding Project - Join FR Team 36120)
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To: RDTF
"There is no alternative therapy, and the poor soul so exposed has no hope other than petitions to God," Tour said. "And that's what drives me," he said, "the hope of saving 1 million people."

If in fact this drug works as they hope, it would make small scale nuclear warfare a much more viable option. Thus the unintended consequence of his 'hope of saving 1 million people' could turn out to be the death of millions.

6 posted on 01/28/2008 7:45:36 AM PST by Between the Lines (I am very cognizant of my fallibility, sinfulness, and other limitations.)
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To: RDTF

Interesting to note that Dr. Denham Harmon’s experiments at the University of Nebraska with lab rats showed average life span increases with the administration of BHT (+30%) and BHA (+50%) over the Control Group. He performed that research in the early 1950s. I suspect he has experimented with antioxidants himself since he is 93 years old and still goes to work every day.


7 posted on 01/28/2008 7:56:23 AM PST by darth
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To: RDTF

If this drug stops free radicals in their path, wouldn’t it make sense to give it to everyone, exploding nukes or not? The article also indicates that the drug will also include substances to speed the repair of cells. Again, wouldn’t this have general health benefits exlusive of exposure to raditation?


8 posted on 01/28/2008 7:59:06 AM PST by Ancesthntr (An ex-citizen of the Frederation trying to stop Monica's Ex-Boyfriend's Wife from becoming President)
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To: Between the Lines

“If in fact this drug works as they hope, it would make small scale nuclear warfare a much more viable option. Thus the unintended consequence of his ‘hope of saving 1 million people’ could turn out to be the death of millions.”

Maybe a more viable option to some groups, but it would be less appealing to the muzzies.


9 posted on 01/28/2008 8:05:55 AM PST by Magic Fingers
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To: RDTF
When I read this post, this Pic for donations came up ... I had to giggle ...


10 posted on 01/28/2008 8:13:42 AM PST by TexGuy (If it has the slimmest of chances of being considered sarcasm ... IT IS!)
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To: Ancesthntr

Bingo!


11 posted on 01/28/2008 8:22:27 AM PST by DakotaGator
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To: Ancesthntr

“raditation”

Uh, “radiation.”

At least I didn’t Carterize “nuclear” into “nukear.”


12 posted on 01/28/2008 8:24:29 AM PST by Ancesthntr (An ex-citizen of the Frederation trying to stop Monica's Ex-Boyfriend's Wife from becoming President)
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To: Between the Lines

This is the same logic that the left uses to try to prevent us from having a missile shield. It is MAD.


13 posted on 01/28/2008 8:27:43 AM PST by FreeAtlanta (Search for Folding Project - Join FR Team 36120)
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To: RDTF

There already is a compound undergoing lots of study, and
is approved for use post radiation therapy for cancer.
It is called amofostine. It is also involved in lots
of research for a protective effect post chemotherapy for
cancer.

One big question, does it protect tumor cells? So far the
answer is no....but who knows....

Finally, I would like to have seen further explanation
of how the nanotubes somehow allowed the BHT,BHA into the
cells. Now that would be pretty revolutionary, cause you
could theoretically tailor certain nanotubes for certain
cells, and get only the drug that is needed to those
cells...i.e. dopamine to striatal nigra neurons, or
antibacterials to only the bacteria, etc...


14 posted on 01/28/2008 8:39:47 AM PST by Getready (Wisdom is more valuable than gold and diamonds, and harder to find.)
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To: RDTF

I would be aglow if there was a few journalists out there who didn’t always have to come up with “cutesy” headlines about scientists being “aglow”.

What the H is wrong with saying “scientists find new drug to treat radiation”?

The dude is supposed to be a news reporter, not a trash romance rag writer...


15 posted on 01/28/2008 9:15:29 AM PST by djf (...and dying in your bed, many years from now, did you donate to FR?)
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