Not quite an admission of guilt, but almost as good for the prosecutor. It is strong evidence that the person is guilty per the following from Law Digest - Law Summaries here:
A blood alcohol test can be refused, but the consequences can be severe. In most states, refusal to take a blood alcohol test is prima facie evidence of drunk driving. In some states refusal to take the test can result in the automatic revocation of a license for a year.
This is NOT true, btw, with the "pre-tests" ie walking a straight line, touching nose, etc. In most states, you CAN refuse due to the lack of effectiveness of such tests in determining intoxication.