I've got essentially the same engine without turbo, and well over 200k miles. But, let's face it - the 3 liter Nissan wasn't your average engine.
True, Nissan put a lot more thought, development time, and research into what has been called “The Japanese Equivalent Of The Chevy Smallblock” than many other makers - but Toyota turboed their 22R engine with similar results (and no problems). Honda turboed a V-twin motorcycle in the 80s, again with no problems.
It *can* be done. Companies just have to not be cheap b******s when it comes to their engine design to get the job done.
I recently bought a 1990 Pathfinder as a knock-about vehicle; it has the same VG30 engine sans turbo, and it has 231K on the clock as we speak today. No issues with it that I’ve been able to discover, and it has a pretty complete service history - just entries of scheduled services over and over. Meanwhile, my neighbor with a 2000 S-10 with the 4.3 has at least five problems a year with that thing.