The other issue with the E model is that it is limited to 6.5 Gs due to its large fuel tanks and attack mission. Less G’s equal longer life.
Good point, cuz even the Strike Eagles are getting a bit old... ;-)
I try not to be sentimental about such things, but it seems to me that the F-15 is one heck of a great plane...and even as good as the F-22 is, would 200 of them equal the 450 F-15s being pulled (Lanchester's Square Law and all)? Plus, technological superiority or not, it means narrower deployment if we have fewer airframes out there--fewer pilots, too.