Here is a short description of some work done by Italian researchers to deal with T cell response to gliaden
link. We may not be able to fix our bad genes, but there may be some hope of blunting the impact of gluten.
The genes, in and of themselves, are not bad. It's clear that they are busy doing what they were supposed to be doing, but in an appropriate environment. Odds are good those genes are protecting us from ingesting rye, barley or primitive wheat with heavy ergot infestation ~ in the far North (Fenno-Scandia) ~ where such things happen much more frequently than in dryer traditional wheat country.
Interesting that they've found a pathway that eliminates the triggering mechanism for the T-cells. Now, if they can also eliminate the "other triggering mechanism" that sets the T-cells up to attack gluten after the ingestion of high levels of alpha amylase ~ that'd be almost magic.