Sure, it won’t fission, but it will get blown to smithereens if you hit it with a big enough explosive. The facility is now said to be a huge hole in the desert. I’m thinking they used either the MOAB, or the MOP(Massive Ordnance Penetrator), or perhaps both.
We don’t know much about the Israeli nuclear program. They may have investigated the idea of the nuclear shaped charge. We figured it out, but never did much of anything with it.