I work in a small rural town that happens to be on an interstate. Some national chain of Adult XXX stores bought some property and low and behold we have a hugh high sign welcoming people to our little town advertising XXX Adult STore. It is disgusting. It needs to be somewhere else. Alot of people and I am one of them would not stop and get even gas at such a exit.
Then the market will decide, and the shop will go out of business.
Sounds like your real problem is with the advertising, which is the domain of your local zoning board.