1) If not for this conquest, there would be no America strong enough to save the world from Hitler, Stalin, and Bin Ladin, allowing it to be completely enslaved THREE TIMES, thank you very much. And...
2) For every AmerIndian society, which of course did it's own share of enslaving, exploiting, and killing OTHER AmerIndian societies, let me make this non-apology: My people were better warriors than you. If you could have, today the continent would be teeming with huge native American cities, had you been more successful in fighting my ancestors. We won...no apologies for that.
The disease thing worked both ways and the Black Death itself, still available in the southwest, might well have come from America through Iceland to Europe. It was before Columbus, which is another myth.
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It was not genocide, it was natural selection