Posted on 07/24/2007 4:53:13 PM PDT by kalee
One of the most surprising characteristics of biological membranes is the fact that both the lipid and the protein molecules, like molecules in any viscous liquid, are constantly in motion. Indeed, the membrane can be considered a two-dimensional liquid in which the protein components ride like boats. However, the lipid molecules in the bilayer must always be oriented with their polar ends at the surface and their nonpolar parts in the central region of the bilayer. The bilayer structure thus has the molecular orientation of a crystal and the fluidity of a liquid. In this liquid-crystalline state, thermal energy causes both lipid and protein molecules to diffuse laterally and also to rotate about an axis perpendicular to the membrane plane. In addition, the lipids occasionally flip from one face of the membrane bilayer to the other and attach and detach from the surface of the bilayer at very slow but measurable rates. Although these latter motions are forbidden to intrinsic proteins, both lipids and proteins can exhibit limited bobbing motions. Within this seemingly random, dynamic mixture of components, however, there is considerable order in the plane of the membrane. This order takes the form of a fluid mosaic of molecular association complexes of both lipids and proteins in the membrane plane. The plane of the biological membrane is thus compartmentalized by domain structures much as the three-dimensional space of the cell is compartmentalized by the membranes themselves. The domain mosaics run in size from tens of nanometres (billionths of a metre) to micrometres (millionths of a metre) and are stable over time intervals of nanoseconds to minutes. In addition to this in-plane domain structure, the two lipid monolayers making up the membrane bilayer frequently have different compositions. This asymmetry, combined with the fact that intrinsic membrane proteins do not rotate about an axis in the membrane plane, makes the two halves of the bilayer into separate domains.
An interesting class of proteins is attached to biological membranes by a lipid that is chemically linked to the protein. Many of these proteins are involved in intra- and intercellular signaling. In some cases defects in their structure render the cells cancerous, presumably because growth-limiting signals are blocked by the structural error.
NICE!
see post 96
That's why I "only" eat beef!!!
PS... long time no see!
Thanks again. Good info. But what is needed to reduce triglycerides? Isn’t it a reduction in eating the types of fat found in beef? (again, this person LOVES beef as do I and routinely eats ground beef, steak, roasts for most of her dietary protein).
I'm not an expert, but my dad had elevated triglycerides. I hope someone will correct me if I'm wrong, but I'm pretty sure that exercise, while not doing much for total or LDL cholesterol, does help to raise HDL and lower triglycerides. I think reducing sugar helps with triglycerides, too.
If she’s adding sugar, then that hurts, IMO. I use either honey or brown sugar. Tell her to be sure and take COQ10. Many cardiologists are prescribing that along with statins. Statins will actually harm muscle (and the heart is one) My husband had a heart attack in 2002 and has been on two cholestral meds but his cholestral didn’t hit optimum until he added red yeast rice. He takes 1,000 mg of the COQ10 too. His new cardiologist said that was a good thing he is doing (COQ10) I started him on it after a “google”. Also I wouldn’t be surprised if stress doesn hurt. My hubby is one of those “A” personalities - “Mr. Perfect”! He is the only one of his family to have heart troubles. Me, on the other hand, have two parents that have high cholestral, high blood pressure, and heart problems. I have none (knock on wood LOL) and I aint no “spraing chiken”
Thanks again - very informative. So the animal fat in beef is “friendly” to the artery walls? But peanut oil, for instance, is NOT friendly to artery walls? Good to know to just reduce fats - of all kinds. How about all the hype about the benefit of fish oil, omega fatty acids or whatever? Is a fish oil supplement a good thing since this person REFUSES to eat any fish whatsoever.
Ok, excellent information too - up the exercise, lower the sugar. Knew someone who had very high triglycerides and that person totally stopped eating beef and started eating LOTS of fish and salads and their triglycerides came back down fast into normal range. But I didn’t know if that was what had to be done or not, and if so - my friend won’t do it. She simply loathes fish of any kind. She is upping the exercise and the eating of salads.
“...there is NO biblical justification for being a vegetarian...”
You are right, of course. The Passover lamb was not a vegetable. Jesus ate the Passover with his disciples. Fish are also not vegetables...Jesus multiplied the loaves and fishes to feed the 5,000. Milk and Honey are not vegetables...a land flowing with milk and honey. The sheet let down and Peter told to slay and eat...a sheet filled with all manner of pig, creepy things, catfish, shellfish etc (representing all the “verboten” creatures under Jewish dietary law).
If God didn’t intend for us to eat animals, why did He make them out of meat? ;^)
Howdy, DirtyHarry! Long time no see indeed. Always good to see you around. I hope things are well with you and yours.
I’m pretty much recuperated from a “funny” heart thing, had episodes since I was 30, but now that the mortal coil is older, takes longer to recuperate.
Hope to get back into pinging in a bit. Things piled up, so I have to do some virtual shoveling for a while.
:-)
That's why I think that a home-raised, home-butchered beef or hog, or venison, are much better for us than the commercial beef. Just my opinion.
Carolyn
Man, Isn't that the truth! I pray for your good health and prosperity!
My MD has added new meds and increased dosage on most others. (hypertension/stress management) Next week I go in for a sleep test. Sleep atmea problems. Hope I can avoid sleep meds.
Thanks for your kind words, Harry!
BTW, I have some ideas to help with sleep if you’re interested you can email me. Natural ones that are totally harmless and have worked with quite a few people.
I rarely have sleep problems so I have only tried a couple on the odd night when sleep doesn’t hit me over the head with a mallet.
That’s why vegetarian’s tend to look sickly and pale. Lack of natural B vitamins in their vegetables (B-12 specifically) and their lack of complete amino acid profiles in the proteins they get from legumes or soy.
I agree with you on this article.
It seems to me that ultra liberals like to do every thing by fad or whats currently hip.
Most of these environmental wackos do not understand that there is a trade off to be paid for the life style they pursue.
What this author dosen’t realize is that she is not striking a blow for the environment.
She is however helping keep smaller farms going and that is a good thing.
She may not also realize that the number of small farms left in the US would not support all the pompous liberals who want to eat locally grown meat.
Personally I wish the Veggie Burger lovers would not switch back to real meat.
The price of Hamburger is high enough.
However, should any of the current Democrats get elected to POTUS we may all need victory gardens and small farms.
Just the lowly opinion of a red state wannabe.
Mollie Katzen, author of the vegetarian bible
Christine Lennon over at Food & Wine
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