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I'll try not to preach a sermon, but simply defined, it means this: Mankind is infected with sin. Because of that, we are all doomed to punishment (eternity in Hell). But Jesus took that punishment upon Himself by suffering the agony of Hell by being crucified. He shed His divine Blood, and now, that Blood can wash away our sins, so that we do not have to suffer that punishment (again, eternity in Hell). Ahh...but the tragedy of man all through these years as he tramples that Blood underfoot, as if it were unholy.