I think that line was from Aliens, (aka Alien 2).....
The first and second movies were good, Alien 3 SUCKED (IMO), and Alien Resurrection was fairly decent....
From John Hurt's cameo in Spaceballs...
Oh no, not again!
[The drop-ship crashes]
Private Hudson:Well that's great, that's just ****in' great man, now what the **** are we supposed to do? We're in some real pretty **** now man... That's it man, game over man, game over, man! Game over! What the **** are we gonna do now? What are we gonna do?
As well as one of the other best lines.
Private Hudson: Hey Vasquez, have you ever been mistaken for a man?
Private Vasquez: No, have you?
The sequal was pretty good. James Cameron did a great job making a big-budget sci-fi film. It was enjoyable, to be sure, but it didn't have the "terror" factor and uncomfortable sense of dread that Ridley Scott's first film did.
Alien was a horror film.
Aliens was a sci-fi film.
I've yet to see the last two.