Had they drawn and printed and ordinary picture of Mohammed and put it in a children's book, my opinion would be entirely different. I still recall a drawing of Mohammed in my gradeschool history book, he was on a horse, it was a side rear angle, he had a sword in his hand and was leading men in battle. However, that was not the case.
There are COUNTLESS more important disagreements the west has with Muslims. This was not one of them.
The worst cartoons were made by a Moslem cleric (Mohammed humping a dog) and that cleric tried to pass it off as one of the Danish cartoons. So clearly some Moslems think so little of Mohammed to use his image profanely. He is only a prophet after all. What is more offensive is the death of the film maker of Submission. That insult actually hurt someone.