Indeed, the very reason why I have a collection of lever guns.
Mine are blued clones of the Winchester 1892 in .45LC. Light easy handling and fine shooters. Available in .38/.357 mag, .44 mag and .454 Casull at very reasonable prices http://www.legacysports.com/product/index.htm
For a longer reach, a Marlin 1985 Cowboy in the venerable but still effective and versatile .45-70 gov. Sweeeeet!
http://www.marlinfirearms.com/Firearms/Cowboy/1895Cowboy.aspx
And, of course, the Marlin 336 available in a variey of finish and reasonable prices. Mine is a vintage 1954 with a ladder tang sight in .30-30 just waiting for the new Hornady 'LeveRevolution' polymer tipped rounds for longer flatter trajectory.
Early American Homeland Defense Rifles
I'll bet you could "ding" a steel plate at 200 yards at a respectable rate of sustained fire with a 30-30 lever action.