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To: Domestic Church
Thanks for posting only the excerpt of interesting dialogue. I read the original. It's a wonder anyone was still conscious after all the introductions and back patting.

The daily reports seem to be getting more specific about the breadth of geography showing active cases and counts of active cases. Drudge is doing a decent job of keeping the recent reports on his page.

A key omission in the excerpt was the comment about NOT giving Tamiflu to someone with a raging case of flu. Such a patient has a very high viral load and giving them Tamiflu would selectively kill the sensitive virus particles, but leave a very large remnant of particles that are insensitive to Tamiflu. The unintended consequence is selective breeding of Tamiflu resistent virus to be spread to the healthy population.

2,855 posted on 11/25/2005 3:32:18 PM PST by Myrddin
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To: Myrddin

"...NOT giving Tamiflu to someone with a raging case of flu..... The unintended consequence is selective breeding of Tamiflu resistent virus to be spread to the healthy population."

You are right! There is a very small window at the beginning to administer tamiflu but outpatient logistics during winter months (first getting the receptionist to squeeze you in for an appointment or waiting in an ER if the receptionist makes you wait a day )will have many getting it too late during a flu season. Hopefully, we will have time to weaken this H5N1 before a species crossover really occurs:



"However, we also found that avian and equine influenza viruses preferentially bind the terminal sialic acid alpha2-3Gal (SA2-3Gal) linkage, while human influenza viruses preferentially bind the SA2-6Gal linkage. Influenza viruses also differ in their recognition of terminal Neu5Ac, Neu5Gc and 9-O-Ac-Neu5Ac. We showed for the first time that SA distribution in animal species does in fact influence influenza virus host range.

http://www.glycoforum.gr.jp/science/word/glycopathology/GD-A06E.html


2,860 posted on 11/25/2005 4:52:10 PM PST by Domestic Church (AMDG...you might as well go for the grape juice instead of the tamiflu!)
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To: Myrddin

I thought that info about Tamiflu quite significant. I know a number of people who have bought Tamiflu and of course no one knows about that.


2,861 posted on 11/25/2005 4:57:17 PM PST by little jeremiah
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