First off, I'm pretty sure there is something which can be given for smallpox after infection, but I could be wrong. Just something I remember from my stay at NBC Warfare School. OTOH, I'm pretty sure that a lab weaponized strain is going to be tougher to deal with; much more lethal and fast acting. I seriously doubt that there are antitoxins or antidotes available to anybody from any nation for these, except what may be carried in a national stockpile for use by the military, only.
Canadian emergency department preparedness for a nuclear, biological or chemical event
Daniel Kollek, MD
http://www.caep.ca/004.cjem-jcmu/004-00.cjem/vol-5.2003/v51-018.htm
I may be mistaken, but I think you can be vaccinated right after infection and have a good chance of surviving. As for a weaponized version I'm not sure. If the weponization was to better disperse it, then it should not matter. If weaponization included selecting a super bug, then were screwed.