[stremba]

Most likely, if you changed your DNA enough, while you would still bear a very close resemblance to other people, you would be rendered incapable of interbreeding with them, and hence by the usual working definition of species, you would no longer be human, or more preciesly you would no longer be a member of the species homo sapiens.

[Stark_GOP]

"Most likely, if you changed your DNA enough, while you would still bear a very close resemblance to other people, you would be rendered incapable of interbreeding with them, and hence by the usual working definition of species, you would no longer be human, or more preciesly you would no longer be a member of the species homo sapiens."
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Most likely you will be dead for the damage to your DNA.
Let's say (for giggles) that you do live to reproductive maturity. You're probably sterile.
Let's allow the possibility that you're not sterile.
You could not select a homo sapien as your mate since you wouldn't produce children.
You would have to search the world in the hope of finding a member of the opposite sex with the same DNA mutation you have that you agree to mate.