I worked at a nuclear power plant in Illinois for eight years. Although I left the industry seven years ago, I have absolutely NO reservations about expanding nuclear power. I do, however, have a deep hatred for electric utility companies (wasteful socialist money grabbers). I have always believed that a genuine intelligent environmentalist/conservationist would firmly embrace nuclear power. Long term spent fuel storage/reprocessing is the major technological issue...but definitely solvable.
I don't think it's major in a technological sense. In a previous life a couple of decades ago I worked on some prototype reprocessing lines that not only partitioned the "waste" (which it really isn't, since it is very useful material), but also allowed implementation of the preliminary steps for full actinide recycle, which you almost have to do to keep volumes reasonably manageable in the long term.
We need only the will to do it and the political courage to move forward on licensing facilities. In addition to LWR material reprocessing, check out the IFR concept. A closed fuel cycle. Very sweet indeed...