Scientists make blood from human stem cells

yahoo news ^ | Jun 16, 2005 | Sonali Paul

[phoenix_004]

MELBOURNE (Reuters) - Australian scientists say they have found a way to make blood cells in volume out of human master cells, which could eventually lead to production of safe blood cells for transfusions and organ transplants.

Synthetically produced red blood cells would, in theory, overcome the concerns about dangerous infections that can be transmitted from blood donors to patients worldwide.

But researchers said it would probably take years for scientists to get to the stage where blood cells could be made in large enough quantities for transfusions.

"What would be nice is if it opens the possibility for the future of making large quantities of blood cells in a controlled environment which could be used to treat patients," said Andrew Elefanty, who led the research at Monash University in Melbourne.

Writing in the U.S. journal Blood, the researchers said they were able to turn human embryonic stem cells into red and white blood cells using a system that makes more blood cells more rapidly and more safely, with fewer animal ingredients, than others have done.

"The other thing we think is important is that the way we've made the cells develop into blood is something which could be applied to other types of cells as well," Elefanty told Reuters.

The team's system was able to stimulate the stem cells specifically into becoming red or white cells.

Elefanty said the research showed that the path that human embryonic stem cells take in becoming blood cells was similar to experiments done in other animals, like mice.

While other researchers have used serum from cows as the medium for growing cells, the Monash team used a cocktail of salt and electrolyte solutions with amino acids and fats.

[Marine_Uncle]

As time goes by we are going to find an almost un-limited capability provided by stem cells. Research in many ways is in it's infancy in this line of science. An analogy would be where perhaps in the second or third year after TI then shortly after Bell labs created the first transistors. At that time it was beyond the wildest dreams of most researchers as how things would progress over the years into what we now take so much for granted. Same scenario will be found to be the case with stem cell research.

[Sacajaweau]

"With fewer animal ingredients".

Very early on, one of the problems with stems cells was using a mouse host...and the potential mixing of species.

We know a lot, but we don't know it all. Look at the premature aging of Dolly. They thought they had it perfected.