A true statement, but it doesn't go far enough.
In terms of population percentage loss, the worst war we ever fought was King Philip's War in 1688. King Philip was an indian chief (also known as Metacomet). The indians burned down whole villages. I had a relative (infant) murdered in his cradle. The Colonists' population was small in 1688 and a good percentage of that population was killed in the war. The indians lost the war.
The Indians sided with the French in the French And Indian War (1753). The indians lost the war.
The indians sided with the British in the Revolution. The indians lost the war.
The indians sided with the British again in the War of 1812. The indians lost the war.
As the Americans moved west, fighting was constant on both sides. The indians started quite a few (but not all) of the fights. The indians lost everytime.
The judgement of history is merciless.