From Genome Comparisons, UCSD Researchers Learn Lessons About Evolution And Cancer

UC San Diego (Press Release) ^ | 13 October 2003

[Stultis]

Achey, breakey chromosomes ping!

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[RightWhale]

evolutionary earthquakes

that's where you grow fur and fangs once a month and hunt down nutria and eat them guts first until the sun comes up

[concerned about politics]

Our creator told us we'd be given grievous ulcers 2000 years ago due to our self absorption. Today, they refer to it as "Stress induced cancer."
Science is really slow. I don't thnk they'll ever catch up. Not in our lifetime, anyway.

[Right Wing Professor]

(Quoting the article) As soon as reconstructions of other tumor genomes are completed, Pevzner and his colleagues will investigate whether the breakpoints implicated in cancers are correlated with the breakpoints evident in human-mouse evolution from their common ancestor 75 million years ago.

If that's their intention, they'll never get the chance. With various mammalian and other genomes on line, there are a dozen research groups looking for evidence of rapid evolutionary change in fragile regions, as we discuss this.

The paper on the 49 human cytochrome c pseudogenes came out in summer 2003. Two weeks ago I set a homework assignment in a freshman honors course to find 10 - 15 of the pseudogenes and construct an evolutionary tree, using them and the two mouse cytochrome c genes. This field is moving so fast, what's revolutionary today is established wisdom tomorrow.

[Aracelis]

Interesting how close many of these fragile areas are to telomeres.

More, including photos.

[antiRepublicrat]

Evolution scientists, when shown clear scientific evidence that their ideas held for the last 20 years are wrong, easily admit that they have some serious revision to do in order to get in line with the facts.

This, folks, is science at its best.

[Stultis]

For the no-scientific-advances-are-based-on-evolution crowd: Note that the theory of fragile breakage (that chromosomes tend to break at certain places rather then randomly) was initially formulated based on the assumption that mice and humans are indeed genetically related (so that differences between their chromosomal arrangements must stem from actual breakages that occured since they shared a common ancestor). Only later was fragile breakage confirmed in modern cells.

[Stultis]

OMG, we're all going to mutate AND die!

[LiteKeeper]

YEC INTREP

[PatrickHenry]

PING. [This ping list is for the evolution side of evolution threads, and sometimes for other science topics. FReepmail me to be added or dropped.]

[balrog666]

My "My Comments" page showed this as post 12 of 11, so we are still having some software problems.

[whattajoke]

good to see you're still around. There was rumor your were zapped yesterday.

[balrog666]

Rumors of my death were greatly exaggerated.

[Shryke]

Rumors of my death were greatly exaggerated.

I watched Gandalf stab you in the chest, you liar. He even had a big lightning bolt charge his sword n' stuff.

[js1138]

In June, Pevzner and UCSD mathematics professor Glenn Tesler predicted the existence of evolutionary 'fault zones' -- hotspots where gene rearrangements are more likely to occur and change the architecture of our genomes.

Hot zone placemarker.

[js1138]

Actually ulcers are a bacterial disease, treatable with antibiotics. The stress theory caused my grandfather a lot of unnecessary stress.

[js1138]

My "My Comments" page showed this as post 12 of 11, so we are still having some software problems.

I see that all the time on FR, not just today. There's a certain pattern of navigation that triggers it. I haven't kept good enough records to duplicate it.

[js1138]

I watched Gandalf stab you in the chest, you liar. He even had a big lightning bolt charge his sword n' stuff.

Last night, while half the crevo posters were busy impailing themselves, I watched a Miyazaki flick, and learned it takes more than one bullet to kill a god.