To: sourcery
Here us the actual abstract from the Science article
Science 2002 Sep 20;297(5589):2053-6
Cleavage of Scarecrow-like mRNA targets directed by a class of
Arabidopsis miRNA.
Llave C, Xie Z, Kasschau KD, Carrington JC.
Center for Gene Research and Biotechnology, and Department of Botany and Plant Pathology,
Oregon State University, Corvallis, OR 97331, USA.
Micro-RNAs (miRNAs) are regulatory molecules that mediate effects by interacting with
messenger RNA (mRNA) targets. Here we show that Arabidopsis thaliana miRNA 39 (also
known as miR171), a 21-ribonucleotide species that accumulates predominantly in inflorescence
tissues, is produced from an intergenic region in chromosome III and functionally interacts with
mRNA targets encoding several members of the Scarecrow-like (SCL) family of putative
transcription factors. miRNA 39 is complementary to an internal region of three SCL mRNAs.
The interaction results in specific cleavage of target mRNA within the region of complementarity,
indicating that this class of miRNA functions like small interfering RNA associated with RNA
silencing to guide sequence-specific cleavage in a developmentally controlled manner.
To: tallhappy; js1138
Well, the science threads wouldn't be dying if they all referred to cleavage.
Cleavage of Scarecrow-like mRNA targets...
Scarecrow cleavage -- better than nothing, I guess.....
13 posted on
09/23/2002 2:46:28 PM PDT by
r9etb
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