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To: ransomnote

questions that I have:

1) normally intact proteins are “digested” in the gut and do not get absorbed into the blood stream. How does a serine protease (protein) bypass this mechanism. I don’t think that taking massive amounts can overwhelm the digestive process.

2) if the protein does get into the blood stream, wouldn’t it typically illicit an immune response after repeated doses?

Guess I may have to read the original paper to get the answers.


20 posted on 09/22/2026 10:12:04 AM PDT by pghkevin (Where have the principles of the founding fathers gone?)
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To: pghkevin

Good questions. I’ve had 9 clot events in my life, all were while I was not taking nattokinase. I’m Protein-S deficient which means my body can’t fight clots.

After my first clot, doctors put me on various prescription blood thinners which I was on for years. While on the prescription blood thinners, I had 8 more clot events. Nothing serious, but clots all the same.

Then I started taking nattokinase around 2016 with no prescription blood thinners and I haven’t had a clot since.

Well, earlier this year I received some health news unrelated to my clotting issue, which was serious enough to make me forget to take nattokinase for a few months. I think I was simply overwhelmed.

And after a few months of not taking nattokinase, I had clusters of clots in my lungs, I was short of breath and had a mild heart attack.

I started taking nattokinase again of course and haven’t had another clot. It definitely works for me. You need 10800 fibrin units of nattokinase and take it with water on an empty stomach.


24 posted on 09/22/2026 10:24:44 AM PDT by scripter ("You don't have a soul, you are a soul. You have a body" C.S. Lewis)
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To: pghkevin

By surviving stomach acid and intestinal processing it elicits innate immune responses ? Natto is also the world’s richest natural dietary source of vitamin K2 which is why I take small (1 Tbsp) amounts daily. That alone pulls in the opposite direction on a molecular level by actually supporting clotting.


29 posted on 09/22/2026 10:48:28 AM PDT by erlayman (E )
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