There’s no mention of Persia destroying Israel in Revelation...if you’re one of those people whose foreign policy prognostications revolve around Biblical eschatology, I think you don’t need to worry.
I keep the idea in the back of my mind (that the Bible tells us what will happen) but I don't view the situation through that lens.
And Persia doesn't have to destroy Israel, they would just have to trigger a conflict in which Gog and Megog attempt it.