Why take an antihistamine that blocks histamine receptors when you can take diamine oxidase enzyme that actually degrades the histamines in the body?
Cytosolic phospholipase A2 (cPLA2) is an enzyme involved in inflammation by releasing arachidonic acid, a precursor for inflammatory mediators.
Arachidonic acid is an omega-6 polyunsaturated fatty acid found in cell membranes that is involved in cell signaling, inflammation, and neurological functions. It is a precursor in the formation of leukotrienes, prostaglandins, and thromboxanes.
Arachidonic acid is a key inflammatory intermediate and can also act as a vasodilator.
I can’t find anything pointing to diamine oxidase degrading or affecting cytosolic phospholipase A2 (cPLA2).