Seems like shooting it from a helicopter would be a better approach.
They are fast, and if you don't get the heart, they aren't going down. And you generally are supposed to be within 40 meters before shooting, so....
Getting killed by a cape buffalo was not on my bucket list, so I took a pass.
Buffalo Bill Cody was a reason the American bison nearly went extinct. He would shoot them while riding in a train. Not funny but at the time it was “OK.”