Dr. Paul Gyorgy, the biochemist who discovered several of the B vitamins, confided in me that he never took vitamin supplements because “all they do is to produce expensive urine.”
The pharmacist recognized me, (his wife was a nursing professor) he smiled and asked me to explain to the clerk why I knew the vitamins didn't work.
I told her the vitamins didn't turn my urine fluorescent yellow. The pharmacist nodded and said, "Give the customer a refund or a replacement, whichever she prefers!"
The mention of B6 was interesting. Linus Pauling mentioned that B6 will result in a desire to talk. It does. He also said B6 would result in nightmares if taken at night (50+mg). I was skeptical and gave it a try. Every two hours, I awoke to vivid nightmares.
I asked my daughter if she remembered dreaming when she woke up. No. I suggested B6 at noon. No results. She then doubled the dosage. No results. Doubled again - no results. I returned to the books and found that a magnesium deficiency would negatively affect B6. So, I gave her some magnesium, and a lower dose of B6. She remembered her dreams.
Another time, a coworker asked me what to take for kidney stones. I responded with B6 and Magnesium. But I warned him to take them in the morning. He took them in the evening and decided to double the dosage. The next morning, he came to work, looking like he had walked through a storm. He didn’t sleep much due to the nightmares.