An absolutely worthless study and conclusion absent analysis of the cause of microbiome compromise.
There is NO SOLUTION to many diseases/conditions without identifying the cause...just a windfall to big pharma. That includes the conditions cited here.
And certainly not in a capsule sold in a store.
In my experience, CFS/ME is due to a combination of two things: vitamin and mineral deficiencies, especially magnesium and Vitamin D, and atypical shingles. The remedy was the right kinds of supplements and changes in diet.