It found that the obese mice’s livers failed to produce proper amounts of coenzyme Q, a molecule essential to energy production.
“We've reframed the problem from a generalized to a site-specific phenomenon, so in the future, instead of broad-spectrum antioxidants, a tailored cocktail of compounds could be developed to effectively and safely reduce mROS, either through decreasing RET, increasing coenzyme Q levels, or both to treat metabolic diseases including type 2 diabetes.”
Ah. That explains it! I’ve got some CoQ10 somewhere around here; I’ll have to dig it up.