High‑dose vitamin D significantly reduces disease activity in early multiple sclerosis onset, clinical trial finds (100,000 IU doses)

Medical Xpress / JAMA ^ | March 24, 2025 | Justin Jackson / Eric Thouvenot et al

[mass55th]

"I have taken over 10,000 IU per day for years and years with absolutely NO ill-effect, but have excellent health for someone who is 80+."

Keep doing what you're doing. Sounds like it works. I'll be 78 this year, the good Lord willing.

[mass55th]

"I read that if you take more than 4,000 IU D3 daily, you need to also take K2 so that calcium is used correctly and does build up on arteries. The MK-7 type of D3 is recommended."

I had to stop taking Calcium supplements many years ago because they found out I have a hyper para-thyroid that produces more calcium than my body needs. My calcium levels are always high in my bloodwork. Other than taking out those glands if it gets worse, there's nothing they can do about it.

[hflynn]

10,000 IUs of vitamin D can become a serious problem unless a doctor is lab testing your blood on a regular basis.

[aimhigh]

what about Vit D toxicity?

Vitamin D toxicity is usually associated with Vitamin D2, not D3. D2 is big pharma's artificial version.

[TTFX]

My calcium levels are always high in my bloodwork.

- - - - - - -

Excess retinol (a type of vitamin a) can cause that. We don’t need to take vitamin a supplements because foods have enough. Some brands of milk and multivitamins have retinol supplements. More info:

Hypercalcemia and vitamin A
https://www.ccjm.org/content/89/2/99.long

[mass55th]

"Hypercalcemia and vitamin A https://www.ccjm.org/content/89/2/99.long"

Thanks for the link.