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From the article’s linked article, also Daily Mail:

For example, some children are born with a condition called fructose-1,6-bisphosphatase deficiency, which means they cannot produce enough of a certain enzyme that the body uses to break down glycerol and turn it into glucose – or sugar.

The rare condition can occur at any point in life and can lead to a range of symptoms depending on its severity, including drowsiness, hypoglycaemia and seizures.

Many people may never realise they have the problem.

Prof Boobis believes that a small child with this condition could become severely unwell if they consumed a large portion of glycerol.

‘In this situation, consuming a lot of glycerol could overwhelm the body and cause a health crisis,’ he says.

‘Because the body could not process the glycerol, this could block the production of all glucose in the body, and the child would experience severe hypoglycaemia.’

In addition, one form of ALDH mutation is G3PDH insufficiency. G3PDH is the cell-produced catalyst which inserts ingested glycerol into the Krebs cycle for oxidation. People with a mutated G3PDH gene can’t clear glycerol, and the mutation is far from rare.