Who funded this?
The number and concentration of chemical impurities is the difference. In addition, analytical methods used to determine concentration may be not adequate and vary from one manufacturing site to another.
I recently tried some Indian-made pills.
They didn’t work. Well, a little. But not sufficiently.
This is a weak study. No info given about the routes of administration of the generics. Was it all oral meds? Some injectables? What were the preexisting health conditions of those who had the adverse reactions? Were the drugs prescribed appropriately?. Did the patients take the meds as prescribed?
But it appears to be a decent sized signal. Bucking for a grant? Job security? American drug manufacturers trying to justify high reimbursement by government agencies?
DOGE dodging? Business professors researching this?
Many American companies use foreign manufacturers to make their drugs, so the distinction between the parent company and the manufacturer has to be made.
Needs further study. Sending crack FDA team...oh,boy.... Moe,Larry, and Curly,,,,
Maybe I’ve been lucky but so far no problems for me with any generics. But this is good information. Thanks.
I have taken one drug long term for many years. Just this last year it started making me sick so I stopped it and wasn’t sick. The brand had changed to Quallent and the order is processed by Express Scripts. Turns out Quallent is a branch of Cigna and didn’t actually make the drug. The drug is made by whatever low cost supplier to Quallent wins the bid at the time and we don’t actually know who made the drug. Cigna assures us they only use suppliers that have FDA approved drugs.
https://www.quallentpharmaceuticals.com/about-us
I imagine one of the differences in the quality of generic drugs is the quality of the manufacturing facility and its equipment. Without pristine conditions you’re more likely to get impurities into the finished goods.
total bullshit ... how come they didn’t look into the poisonous “generics” manufactured in China? ... you know, the ones being recalled all the time because they contain carcinogenic contaminates? ... actually, not JUST the generics, but in some cases the name brand medications!
I’d take Indian-made drugs any day of the week over ANYTHING made in China, and actually I do: i routinely import Indian-made drugs ... a recent extremely nasty sinus infection was completely knocked out with Indian-made Augmentin ...