The pilots didn’t loose control, they were incapacitated by something,,,,maybe an auxiliary patient Oxy tank ruptured which would explain the fiery explosion midair. It would have incapacitated the crew.
That makes sense. Clearly the plane was knocked out of the sky by something.
A reporter described it as a fireball from the sky, but it looked like more of a smoke trail to me. It came in at such a steep dive angle to indicate that it was probably totally out of control.