Israel has bombed Syrian arms depots and occupied a slice of the Golan Heights formerly occupied by Syrian troops. As those moves suggest, Israel now has much greater freedom of action in Syria due to the lack of a coherent Syrian state.
That there is more latitude doesn't mean the situation is safer. Those weapons are easily resupplied, as we've seen.
Hopefully Trump can reestablish the chokehold on Iran, but with radical Sunnis now in charge of Syria, that may not matter so much.