This medicine, sacubitril/valsartan (ENTRESTO), is available today and the high dose costs the same as the low dose, strangely. It would be taken while undergoing chemo.
It was associated with a 77% decrease in relative risk of any further heart damage. It was well tolerated.
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2 posted on
12/04/2024 7:35:43 PM PST by
ConservativeMind
(Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
To: ConservativeMind
Thanks for posting this. My youngest son, now aged 53, went through 6 months of chemotherapy in 2019 after having surgery for colon cancer. He was recently diagnosed with Hypertrophic cardiomyopathy, and has an appointment at the heart clinic at Rochester (New York) Regional Hospital on December 13th to be tested to see if he was born with this condition, or if it was caused by out-of-control blood pressure. After seeing this article, I'm now wondering if the chemo treatments could be the culprit. I just shared this article's info with him, and he told me that one of the chemo drugs they gave him was Oxaliplatin, which we just discovered can cause heart problems that can lead to death.
Since July, he's has two instances of congestive heart failure, and one a-fib episode. He was operated on November 2nd for a blockage caused by an internal hernia. They had to do a resection in order to get to the hernia to repair it. While in ICU and again after being moved to a regular room, he had three a-fib episodes. They finally got him stabilized, and he was discharged after almost two weeks. He saw his family doctor a couple of days later, and was put on Eliquis (blood thinner), Entresto, and Farxiga. On November 25, he ended up back in the hospital with internal bleeding caused by an ulceration in his small bowel. They repaired it via an endoscopy/bronchoscopy. This past Saturday afternoon, he had another a-fib episode so I took him to the ER. His heart rate was up to 144 while there. Before the doctor came in to see him, his a-fib had ended so they sent him home, with no change in his meds. He has an appointment on Monday to see his Cardiologist.
3 posted on
12/04/2024 9:04:00 PM PST by
mass55th
(“Courage is being scared to death, but saddling up anyway.” ― John Wayne)
To: ConservativeMind
I’ve been taking Entresto for a little over a month now after my last hospitalization for Afib. I am still in rhythm and my BP is doing well. My heart rate went from the 40’s after the cardioversion to 60-70’s now and I’m feeling stronger. I’m also no longer on Metoprolol Tartrate or Losartin.
4 posted on
12/06/2024 4:16:24 PM PST by
boatbums
(When you dwell in the shelter of the Most High, you will rest in the shadow of the Almighty. )
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